In 1981, Virginia Vallejo (Penelope Cruz), a famous Colombian journalist and TV news anchorwoman is invited to a VIPs party in the ranch of Pablo Escobar (Javier Bardem), a famous drug lord. Seduced by his charisma, Virginia begins a passionate love affair with Escobar despite him being married but she starts to understand Escobar’s real power controlling an empire of crime in Colombia and tries to put a stop to him.